Found 24275 Biochemistry Products.
This volume offers a broad and interdisciplinary view of modern approaches to drug discovery as used by pharmaceutical companies and research institutes. It comprehensively covers proteomics, bioinformatics, screening techniques such as high-throughput-, natural compounds-, and NMR-based-screenings, combinatorial chemistry, compound library design, ligand- and structure-based drug design and pharmacokinetic approaches. Each of the thirteen chapters reviews the theory, background and application of a key technology in drug discovery, complemented by an extensive list of references to the original literature. This concise source of information will be useful for researchers, both in industry and academia, as well as students in the fields of medicinal, pharmaceutical and computational chemistry, bioinformatics, biochemistry, molecular biology and pharmacology.
Price : $171.71
$171.71
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Exercise Metabolism, Second Edition, provides a systematic, in-depth examination of the regulation of metabolic processes during exercise. Exercise physiologists, exercise biochemists, and biochemists will find this book a comprehensive reference, using the up-to-date information and the nearly 1,000 references in their own research and writing. In addition, graduate students in these disciplines can learn firsthand about the various regulations of metabolic processes during exercise as they prepare for careers in exercise physiology or biochemistry.Written by internationally recognized researchers, Exercise Metabolism, Second Edition, is both revised and expanded while retaining the essential elements of the first edition. It delves into the mobilization and utilization of substratesâglucose, lipid, and proteinâduring physical activity, and it explores metabolic factors in fatigue and metabolic adaptations to endurance training.Chapter 1 provides an overview of exercise metabolism. Metabolism during high-intensity exercise and the transition from rest to exercise are covered in chapter 2, which details the so-called anaerobic energy pathways. Chapter 3 discusses the effects of exercise on carbohydrate metabolism in skeletal muscle, while chapter 4 provides an overview of the important metabolic functions of the liver during exercise. Chapter 5 is a new chapter that addresses lactate transport in skeletal muscle, given the increased understanding of this topic since the first edition was published. Chapters 6 and 7 summarize the effects of exercise on lipolysis in adipose tissue and lipid metabolism in skeletal muscle, respectively. The contribution of protein and amino acids to exercise metabolism is discussed in chapter 8. Finally, metabolic factors in fatigue and the metabolic adaptations to endurance training are reviewed in chapters 9 and 10, respectively. Chapter-ending summaries help to condense the information and facilitate understanding.Exercise Metabolism, Second Edition, is a valuable reference to exercise physiologists, exercise biochemists, and biochemists, and it serves as an ideal text for graduate students in these disciplines.
Price : $51.27
$51.27
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Summarizes the advances in enzymology over the last 50 years. The book presents up-to-date reviews on cofactor and metal ion catalysis in enzymes, on free radical reactions in enzymes, and on the chemistry of P-450s. It emphasizes phosphoryl transfer reactions.
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Aquatic Photosynthesis is a comprehensive guide to understanding the evolution and ecology of photosynthesis in aquatic environments. This second edition, thoroughly revised to bring it up to date, describes how one of the most fundamental metabolic processes evolved and transformed the surface chemistry of the Earth. The book focuses on recent biochemical and biophysical advances and the molecular biological techniques that have made them possible.In ten chapters that are self-contained but that build upon information presented earlier, the book starts with a reductionist, biophysical description of the photosynthetic reactions. It then moves through biochemical and molecular biological patterns in aquatic photoautotrophs, physiological and ecological principles, and global biogeochemical cycles. The book considers applications to ecology, and refers to historical developments. It can be used as a primary text in a lecture course, or as a supplemental text in a survey course such as biological oceanography, limnology, or biogeochemistry.
Price : $55.85
$55.85
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The contamination of soils and groundwater by petroleum is a growing problem, not only for the oil-producing countries. This book describes the possible approaches for preventing such pollution or, if it occurs, for its reclamation. It combines the knowledge and experience of scientists - providing scientific methods - on the one hand, and engineers - to show what is feasible taking costs into account - on the other. For the various approaches and processes, the experimental analysis, computer model development, and field implementation are discussed. Also considered is the migration of petroleum in soils, and its interaction with the soil and with bacteria.
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This text explains the key biochemical and cell biological principles behind some of today's most commonly used applications of molecular genetics, using clear terms and well-illustrated flow schemes. The book is divided into several sections and moves from basic to advanced topics while providing a concise overview of fundamental concepts in modern biotechnology. Each chapter concludes with a Laboratory Practicum describing a hypothetical research objective and the sequence of steps that are most often used to investigate biological questions using molecular genetic methods. In addition, the book provides informative summaries of the latest advances in molecular genetics, using attractive illustrations and a comprehensive reference list.This text also introduces the use of Internet resources through the World Wide Web as a powerful new tool in molecular genetic research. Seven appendices are included in the book, providing a convenient information resource for properties of nucleic acids, protein and restriction enzymes, a description of common E. coli genetic markers and gel electrophoresis parameters, as well as a list of useful Internet address sites.
Price : $92.47
$92.47
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The application of computational methods to DNA and protein science is an exciting development in biology. "Bioinformatics: Sequence and Genome Analysis" is a comprehensive introduction to this emerging field of study. The book has many valuable features. It is written for biologists who want to understand methods of sequence and structure analysis and how the necessary computer programs work. Sequence alignment, structure prediction, phylogenetic and gene prediction, database searching, and genome analysis are clearly explained and illustrated. Underlying algorithms and assumptions are also explained for the non-specialist, and examples are presented in simple numerical terms rather than complex formulas and notation. Theoretical underpinnings are linked to biological problems and their solutions, while extensive tables provide descriptions and Web sources for a broad range of publicly available software. Based on the author's experience as a molecular geneticist and bioinformaticist at the University of Arizona, this is an educational book, useful as a laboratory reference for investigators and also as a teaching reference for graduate and undergraduate students.
Price : $59.89
$59.89
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The Affymetrix GeneChip® system is one of the most widely adapted microarray platforms. However, due to the overwhelming amount of information available, many Affymetrix users tend to stick to the default analysis settings and may end up drawing sub-optimal conclusions. Written by a molecular biologist and a biostatistician with a combined decade of experience in practical expression profiling experiments and data analyses, Gene Expression Studies Using Affymetrix Microarrays tears down the omnipresent language barriers among molecular biology, bioinformatics, and biostatistics by explaining the entire process of a gene expression study from conception to conclusion. Truly Multidisciplinary: Merges Molecular Biology, Bioinformatics, and Biostatistics This authoritative resource covers important technical and statistical pitfalls and problems, helping not only to explain concepts outside the domain of researchers, but to provide additional guidance in their field of expertise. The book also describes technical and statistical methods conceptually with illustrative, full-color examples, enabling those inexperienced with gene expression studies to grasp the basic principles. Gene Expression Studies Using Affymetrix Microarrays provides novices with a detailed, yet focused introductory course and practical user guide. Specialized experts will also find it useful as a translation dictionary to understand other involved disciplines or to get a broader picture of microarray gene expression studies in general. Although focusing on Affymetrix gene expression, this globally relevant guide covers topics that are equally useful for other microarray platforms and other Affymetrix applications.
Price : $77.60
$77.60
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The beauty and variety of plants has fascinated mankind for thousands of years, and this fascination continues today as plant developmental biologists discover mechanisms that control the establishment of specialized cell types, tissues, and organs from the fertilized egg during a plantâs life. In Plant Developmental Biology: Methods and Protocols, expert researchers provide a collection of protocols for many of the common experimental approaches in plant developmental biology, including diverse methods that range from grafting over bimolecular fluorescence complementation to chromatin immunoprecipitation. Chapters are divided into six major parts: growth protocols, manipulation of gene activity, assaying developmental phenotypes, assaying gene activity, testing protein-protein interactions, and probing chromatin. Composed in the highly successful Methods in Molecular Biology⢠series format, each chapter contains a brief introduction, step-by-step methods, a list of necessary materials, and a Notes section which shares tips on troubleshooting and avoiding known pitfalls. Comprehensive and revolutionary, Plant Developmental Biology: Methods and Protocols is an essential guide for all plant developmental geneticists, biochemists, and researchers in stress physiology and plant nutrition.
Price : $121.96
$121.96
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Like the cracking of the genetic code and the creation of the atomic bomb, the discovery of how the brain's neurons work is one of the fundamental scientific developments of the twentieth century. The discovery of neurotransmitters revolutionized the way we think about the brain and what it means to be human yet few people know how they were discovered, the scientists involved, or the fierce controversy about whether they even existed. The War of the Soups and the Sparks tells the saga of the dispute between the pharmacologists, who had uncovered the first evidence that nerves communicate by releasing chemicals, and the neurophysiologists, experts on the nervous system, who dismissed the evidence and remained committed to electrical explanations.The protagonists of this story are Otto Loewi and Henry Dale, who received Nobel Prizes for their work, and Walter Cannon, who would have shared the prize with them if he had not been persuaded to adopt a controversial theory (how that happened is an important part of this history). Valenstein sets his story of scientific discovery against the backdrop of two world wars and examines the fascinating lives of several scientists whose work was affected by the social and political events of their time. He recounts such stories as Loewi's arrest by Nazi storm troopers and Dale's efforts at helping key scientists escape Germany. The War of the Soups and the Sparks reveals how science and scientists work. Valenstein describes the observations and experiments that led to the discovery of neurotransmitters and sheds light on what determines whether a novel concept will gain acceptance among the scientific community. His work also explains the immense importance of Loewi, Dale, and Cannon's achievements in our understanding of the human brain and the way mental illnesses are conceptualized and treated. (January 2006)
Price : $27.00
$27.00
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